BDBM639376 US20230391768, Compound I-20

SMILES CCN1CCN(Cc2cc(NC(=O)c3ccc(CC)c(c3)-c3ccc4nc(NC(=O)C5CC5)cn4n3)cc(c2)C(F)(F)F)CC1

InChI Key InChIKey=SKCUFRJSZBQDLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639376   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM639376(US20230391768, Compound I-20)
Affinity DataIC50: 399nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent