BDBM639370 US20230391768, Compound I-14

SMILES Cc1ccc(cc1-c1ccc2nc(NC(=O)C3CC3)cn2n1)C(=O)Nc1cc(CN2CCN(CC3CC3)CC2)cc(c1)C(F)(F)F

InChI Key InChIKey=NFOVXAFXDZNRLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639370   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM639370(US20230391768, Compound I-14)
Affinity DataIC50: 772nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent