BDBM639330 7-(5-cyano-2-fluoro-phenyl)- N-[(1R,3S)-3- hydroxycyclopentyl] benzofuran-2-carboxamide::US20230391758, Compound 32

SMILES O[C@H]1CC[C@H](C1)NC(=O)c1cc2cccc(-c3cc(ccc3F)C#N)c2o1

InChI Key InChIKey=LSQRZAKPLQTKOO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639330   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639330(7-(5-cyano-2-fluoro-phenyl)- N-[(1R,3S)-3- hydroxy...)
Affinity DataEC50:  5nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent