BDBM639319 2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{[2-methyl-3-(2-oxopyrrolidin-1-yl)phenyl]sulfonyl-S-alaninate hydrochloride::US20230391761, Reference 2

SMILES CN(C)CCOC(=O)[C@H](CNC(=O)c1ccc(Cl)s1)NS(=O)(=O)c1cccc(N2CCCC2=O)c1C

InChI Key InChIKey=MLVRJRSVNIXHHG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 639319   

TargetCoagulation factor X(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)
Affinity DataIC50: 1.10nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
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TargetProthrombin(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)
Affinity DataIC50: 15nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
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TargetCoagulation factor XI(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)
Affinity DataIC50: 5.00E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetSerine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)
Affinity DataIC50: 3.20E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
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TargetPlasminogen(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)
Affinity DataIC50: 5.00E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetTissue-type plasminogen activator(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)
Affinity DataIC50: 1.60E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetKallikrein-1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)
Affinity DataIC50: 1.10E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent