BDBM639173 (E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-(1-ethyl-1H-tetrazol-5-yl)methyl)-1-(4-(trifluoromethyl)benzyl)-1,3,5-triazin-2,4-dione::US20230391736, Example 18

SMILES CCn1nnnc1Cn1c(=O)[nH]\c(=N/c2cc3cn(C)nc3cc2Cl)n(Cc2ccc(cc2)C(F)(F)F)c1=O

InChI Key InChIKey=IRDCDJYIAVGJGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639173   

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandPNGBDBM639173((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
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Date in BDB:
1/28/2024
Entry Details
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