BDBM639158 (E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-(1-ethyl-1H-1,tetrazol-5-yl)methyl)-1-(2,4,5-trifluorobenzyl)-1,3,5-triazin-2,4-dione::US20230391736, Example 17

SMILES CCn1nnnc1Cn1c(=O)[nH]\c(=N/c2cc3cn(C)nc3cc2Cl)n(Cc2cc(F)c(F)cc2F)c1=O

InChI Key InChIKey=WQYWUTMBHBBLCS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 639158   

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandPNGBDBM639158((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 160nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandPNGBDBM639158((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM639158((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed