BDBM639156 US20230391736, Example 1::US20230391736, Example 16

SMILES Cn1cc2cc(\N=c3/[nH]c(=O)n(Cc4nnn[nH]4)c(=O)n3Cc3cc(F)c(F)cc3F)c(Cl)cc2n1

InChI Key InChIKey=MXEYFHLZFXXVGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 639156   

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandPNGBDBM639156(US20230391736, Example 16 | US20230391736, Example...)
Affinity DataIC50: 120nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandPNGBDBM639156(US20230391736, Example 16 | US20230391736, Example...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandPNGBDBM639156(US20230391736, Example 16 | US20230391736, Example...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent