BDBM6389 3-[(5-{6-[(3-methoxyphenyl)amino]pyrazin-2-yl}pyridin-3-yl)amino]propan-1-ol::3-[[5-[6-[(3-Methoxyphenyl)amino]pyrazinyl]-3-pyridinyl]-1-propanol::Pyrazine-Pyridine Biheteroaryl 15

SMILES COc1cccc(Nc2cncc(n2)-c2cncc(NCCCO)c2)c1

InChI Key InChIKey=TYOTYOPLSRQPGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6389   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6389(3-[[5-[6-[(3-Methoxyphenyl)amino]pyrazinyl]-3-pyri...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6389(3-[[5-[6-[(3-Methoxyphenyl)amino]pyrazinyl]-3-pyri...)
Affinity DataIC50: 740nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed