BDBM638559 US11834467, Example 154

SMILES F[C@H]1C[C@H]1C(=O)Nc1cn2cc(ncc2n1)-c1c(Cl)c(F)c(Nc2ccn[nH]2)c2[nH]ncc12

InChI Key InChIKey=VTTVFASUUWIQMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 638559   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM638559(US11834467, Example 154)
Affinity DataIC50: 200nMAssay Description:HPK1 kinase activity was measured by Promega's ADP-Glo kinase assay. In this assay, 5 ng of recombinant human HPK1 (signalchem) is incubated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2024
Entry Details
Go to US Patent