BDBM638416 US11834467, Example 11

SMILES Nc1c(F)cc2[nH]ncc2c1-c1ccc2nc(NC(=O)[C@@H]3C[C@@H]3F)cn2n1

InChI Key InChIKey=HVGSURWHWDPGGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 638416   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM638416(US11834467, Example 11)
Affinity DataIC50: 1.00E+3nMAssay Description:HPK1 kinase activity was measured by Promega's ADP-Glo kinase assay. In this assay, 5 ng of recombinant human HPK1 (signalchem) is incubated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2024
Entry Details
Go to US Patent