BDBM637771 4-(2-((2-(2- cyclopropyl-1H- imidazol-1- yl)pyridin-4- yl)oxy)ethoxy) benzonitrile::US11834430, Compound 89

SMILES N#Cc1ccc(OCCOc2ccnc(c2)-c2ccnn2C2CC2)cc1

InChI Key InChIKey=PBTWVSMZIAJRGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637771   

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM637771(US11834430, Compound 89 | 4-(2-((2-(2- cyclopropyl...)
Affinity DataIC50: 2.80nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
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