BDBM637715 (S)-3-chloro-4-(2- (3-(2-methyl-1H- imidazol-1- yl)phenoxy)propoxy) benzonitrile::US11834430, Compound 33

SMILES C[C@@H](COc1ccc(cc1Cl)C#N)Oc1cccc(c1)-n1ccnc1C

InChI Key InChIKey=SUPDUAUQKZYSFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637715   

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM637715(US11834430, Compound 33 | (S)-3-chloro-4-(2- (3-(2...)
Affinity DataIC50: 1.5nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent