BDBM636981 N-(4-(4-(5- (cyclopentyl(hydroxy)methyl)furan-2-yl)- 1H-1,2,3-triazol-1-yl)-3-(6- azaspiro[2.5]octan-6- yl)phenyl)ethanesulfonamide::US20230382889, Compound 123

SMILES CCS(=O)(=O)Nc1ccc(c(c1)N1CCC2(CC2)CC1)-n1cc(nn1)-c1ccc(o1)C(O)C1CCCC1

InChI Key InChIKey=LWDXGMMGJQNFQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636981   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM636981(US20230382889, Compound 123 | N-(4-(4-(5- (cyclope...)
Affinity DataIC50: 4.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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