BDBM636954 N-(4-(1-(6-(4,4-difluoropiperidin-1- yl)pyrazin-2-yl)-1H-1,2,3-triazol-4-yl)-3- (6-azaspiro[2.5]octan-6-yl)phenyl)-2- hydroxyethane-1-sulfonamide::US20230382889, Compound 96

SMILES OCCS(=O)(=O)Nc1ccc(-c2cn(nn2)-c2cncc(n2)N2CCC(F)(F)CC2)c(c1)N1CCC2(CC2)CC1

InChI Key InChIKey=CCTCNDZBBMRJQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636954   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM636954(US20230382889, Compound 96 | N-(4-(1-(6-(4,4-diflu...)
Affinity DataIC50: 4.40nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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