BDBM636947 US20230382889, Compound 90a::US20230382889, Compound 90b

SMILES OCCS(=O)(=O)Nc1ccc(c(c1)N1CCC2(CC2)CC1)-n1cc(nn1)-c1cccc(n1)C(O)C1CCCC1

InChI Key InChIKey=ILZKSTSQDOTPSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 636947   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM636947(US20230382889, Compound 90a | US20230382889, Compo...)
Affinity DataIC50: 5.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM636947(US20230382889, Compound 90a | US20230382889, Compo...)
Affinity DataIC50: 5.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent