BDBM636874 N-(4-(5-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-yl)-4H-1,2,4-triazol-3-yl)-3- (6-azaspiro[2.5]octan-6-yl)phenyl)-2- hydroxyethane-1-sulfonamide::US20230382889, Compound 8

SMILES OCCS(=O)(=O)Nc1ccc(-c2nnc([nH]2)-c2cccc(n2)N2CCC(F)(F)CC2)c(c1)N1CCC2(CC2)CC1

InChI Key InChIKey=PXFJGTXBMZTFSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636874   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM636874(US20230382889, Compound 8 | N-(4-(5-(6-(4,4-difluo...)
Affinity DataIC50: 5.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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