BDBM636830 2-(2,6-dichlorophenyl)-1-[(1S,3R)-6- fluoro-3-(hydroxymethyl)-5-[trans-(1- hydroxy-1-methyl-ethyl)cyclopropyl]- 1-methyl-3,4-dihydro-1H-isoquinolin- 2-yl]ethenone, Isomer 2::US20230382869, Compound Table1.11::US20230382869, Compound Table1.4

SMILES C[C@@H]1N([C@@H](CO)Cc2c1ccc(F)c2C1(CC1)C(C)(C)O)C(=O)Cc1c(Cl)cccc1Cl

InChI Key InChIKey=QMWIFKHZTDJQFB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 636830   

TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM636830(US20230382869, Compound Table1.4 | 2-(2,6-dichloro...)
Affinity DataEC50:  5.19nMAssay Description:Test compound is serially diluted (1:2) with DMSO into assay plates (ProxiPlate-384 Plus, PerkinElmer) using acoustic dispensing (Labcyte) to provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM636830(US20230382869, Compound Table1.4 | 2-(2,6-dichloro...)
Affinity DataEC50:  12.3nMAssay Description:Test compound is serially diluted (1:2) with DMSO into assay plates (ProxiPlate-384 Plus, PerkinElmer) using acoustic dispensing (Labcyte) to provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent