BDBM636828 2-(2,6-Dichlorophenyl)-1-[(1S,3R)-5- [4,4-difluoro-3-hydroxy-3-methyl- butyl]-3-(hydroxymethyl)-1-methyl- 3,4-dihydro-1H-isoquinolin-2- yl]ethenone, Isomer 1::US20230382869, Compound Table1.2::US20230382869, Compound Table1.9

SMILES C[C@@H]1N([C@@H](CO)Cc2c(CCC(C)(O)C(F)F)cccc12)C(=O)Cc1c(Cl)cccc1Cl

InChI Key InChIKey=KQGJFYRCVDYVFK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 636828   

TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM636828(US20230382869, Compound Table1.2 | US20230382869, ...)
Affinity DataEC50:  7.96nMAssay Description:Test compound is serially diluted (1:2) with DMSO into assay plates (ProxiPlate-384 Plus, PerkinElmer) using acoustic dispensing (Labcyte) to provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM636828(US20230382869, Compound Table1.2 | US20230382869, ...)
Affinity DataEC50:  12.7nMAssay Description:Test compound is serially diluted (1:2) with DMSO into assay plates (ProxiPlate-384 Plus, PerkinElmer) using acoustic dispensing (Labcyte) to provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent