BDBM636180 US20230365541, Compound 29::methyl-4-(7-chloro-2,4-dimethyl-5-(((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)benzo[d][1,3]dioxol-2-yl)piperidine-1-carboxylate

SMILES COC(=O)N1CCC(CC1)C1(C)Oc2c(O1)c(C)c(cc2Cl)C(=O)NCc1c(SC)cc(C)[nH]c1=O

InChI Key InChIKey=SQLMKVXDKGRKGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636180   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM636180(methyl-4-(7-chloro-2,4-dimethyl-5-(((6-methyl-4-(m...)
Affinity DataIC50: 0.440nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
Go to US Patent