BDBM636167 US20230365541, Compound 9, isomer 2

SMILES CO[C@H]1C[C@@H](C1)N[C@H]1CC[C@H](CC1)C1(C)Oc2c(O1)c(C)c(cc2Cl)C(=O)NCc1c(SC)cc(C)[nH]c1=O

InChI Key InChIKey=CIJHVAWUSUTLMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636167   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM636167(US20230365541, Compound 9, isomer 2)
Affinity DataIC50: 0.480nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
Go to US Patent