BDBM636163 US20230365541, Compound 11, isomer 1::US20230365541, Compound 7, isomer 1

SMILES CSc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Cl)c2O[C@@](C)(Oc2c1C)C1CCN(CC1)C(=O)C1CC1

InChI Key InChIKey=DKBJHQQCVQYPDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 636163   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM636163(US20230365541, Compound 7, isomer 1 | US2023036554...)
Affinity DataIC50: 0.520nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM636163(US20230365541, Compound 7, isomer 1 | US2023036554...)
Affinity DataIC50: 0.730nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
Go to US Patent