BDBM636157 US20230365541, Compound 3, isomer 2

SMILES CSc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Cl)c2OC(C)(Oc2c1C)[C@H]1CC[C@@H](CC1)NCC1(C)COC1

InChI Key InChIKey=ZHMRARCDOBQZEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636157   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM636157(US20230365541, Compound 3, isomer 2)
Affinity DataIC50: 0.510nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
Go to US Patent