BDBM635746 US20230364079, Example 146

SMILES COc1ccccc1C(F)(F)c1ccc(cc1)-c1nc(n2ccnc(N)c12)C12CCC(CO)(CC1)OC2

InChI Key InChIKey=CESQHIFBQQEBBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635746   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635746(US20230364079, Example 146)
Affinity DataIC50: 3.92nMAssay Description:1) 1× kinase reaction buffer was prepared from 1 volume of 5× kinase reaction buffer and 4 volumes of water, 1 mM dithiothreitol, 5 mM magnesium chlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent