BDBM635583 US20230364079, Example 5::US20230364079, Example 7

SMILES COc1cccc(Oc2ccc(cc2)-c2nc(C3CCC(CO)OC3)n3ccnc(N)c23)c1F

InChI Key InChIKey=XYEAZFFSYKCIRD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 635583   

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent