BDBM635407 1-(1,1-Difluoro-2-methylpropan-2-yl)-N-{2- fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo[1,2-a]pyridin-6-yl]phenyl}pyrazole-4- carboxamide::US11814384, Example 124

SMILES Cc1cc(F)c(NC(=O)c2cnn(c2)C(C)(C)C(F)F)cc1-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=IVEYRQKPXZLZTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635407   

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635407(1-(1,1-Difluoro-2-methylpropan-2-yl)-N-{2- fluoro-...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2024
Entry Details
US Patent