BDBM63525 2-(3-nitrophenyl)-5-phenyl-1,3,4-oxadiazole::2-phenyl-5-(3-nitrophenyl)-1,3,4-oxadiazole (2j)::MLS000709882::SMR000287045::cid_577329

SMILES [O-][N+](=O)c1cccc(c1)-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=PPAQPCTUYHOPLY-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 63525   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63525(MLS000709882 | SMR000287045 | cid_577329 | 2-(3-ni...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetCathepsin L(Goat)
Kurukshetra University

LigandPNGBDBM63525(MLS000709882 | SMR000287045 | cid_577329 | 2-(3-ni...)
Affinity DataKi:  63.4nM ΔG°:  -10.2kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM63525(MLS000709882 | SMR000287045 | cid_577329 | 2-(3-ni...)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.51kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin H(Goat)
Kurukshetra University

LigandPNGBDBM63525(MLS000709882 | SMR000287045 | cid_577329 | 2-(3-ni...)
Affinity DataKi:  3.85E+3nM ΔG°:  -7.68kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed