BDBM635210 US11814367, Compound 659

SMILES CC(C)c1c(F)cc(cc1F)[C@@H](NC(=O)[C@@H]1C[C@@H](F)CN1S(=O)(=O)Cc1cnn[nH]1)c1ccccc1

InChI Key InChIKey=RLUIYLQMUNWBNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635210   

TargetGlycogen [starch] synthase, muscle(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM635210(US11814367, Compound 659)
Affinity DataIC50: 331nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
Go to US Patent

TargetGlycogen [starch] synthase, liver(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM635210(US11814367, Compound 659)
Affinity DataIC50: 1.75E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
Go to US Patent