BDBM635147 US11814367, Compound 596

SMILES Cn1nc(CC(=O)N2C[C@H](F)C[C@H]2C(=O)N[C@@H](c2ccccc2)c2ccc(c(F)n2)C2(C)CC2)c2ccccc12

InChI Key InChIKey=QKBABOAMYISMPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635147   

TargetGlycogen [starch] synthase, muscle(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM635147(US11814367, Compound 596)
Affinity DataIC50: 20nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
Go to US Patent

TargetGlycogen [starch] synthase, liver(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM635147(US11814367, Compound 596)
Affinity DataIC50: 9.67E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
Go to US Patent