BDBM635055 US11814367, Compound 504

SMILES F[C@@H]1C[C@H](N(C1)C(=O)Cn1cnc2ccccc12)C(=O)N[C@@H](c1ccccc1)c1ccc(C2CC(F)(F)C2)c(F)n1

InChI Key InChIKey=MQTYAVBLUZSAPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635055   

TargetGlycogen [starch] synthase, liver(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM635055(US11814367, Compound 504)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
Go to US Patent

TargetGlycogen [starch] synthase, muscle(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM635055(US11814367, Compound 504)
Affinity DataIC50: 3nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
Go to US Patent