BDBM634366 8,14-dioxa-4,5,10,19,20-::US20230357269, Example 51

SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cnn(CCO1)c4)c3c2

InChI Key InChIKey=WKAUBRXJHPTAPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634366   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM634366(US20230357269, Example 51 | 8,14-dioxa-4,5,10,19,2...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
Go to US Patent