BDBM634350 4-(azetidin-1-yl)-8,14-dioxa-10,19,20-::US20230357269, Example 35

SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cc(CO1)cc(c4)N1CCC1)c3c2

InChI Key InChIKey=QEELUUWDIUXKFF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634350   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
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US Patent
LigandPNGBDBM634350(US20230357269, Example 35 | 4-(azetidin-1-yl)-8,14...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
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