BDBM634340 4-[(3R)-3-hydroxypyrrolidin-1-yl]-8,14-dioxa-::US20230357269, Example 25

SMILES O[C@@H]1CCN(C1)c1cc2COC(=O)NCCCOc3ccc4[nH]nc(-c(c2)c1)c4c3

InChI Key InChIKey=AAJISJWUDFORLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634340   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
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US Patent
LigandPNGBDBM634340(US20230357269, Example 25 | 4-[(3R)-3-hydroxypyrro...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
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