BDBM634322 8,14-dioxa-5,10,19,20-::US20230357269, Example 7

SMILES O=C1NCCCOc2ccc3[nH]nc(-c4ccnc(CO1)c4)c3c2

InChI Key InChIKey=XVLGZPGVLXOVRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634322   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
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US Patent
LigandPNGBDBM634322(US20230357269, Example 7 | 8,14-dioxa-5,10,19,20-)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
Go to US Patent