BDBM63417 MLS000730236::N-[1-(4-fluorobenzyl)-1H-pyrazol-4-yl]-5-(2-furyl)isoxazole-3-carboxamide::N-[1-(4-fluorobenzyl)pyrazol-4-yl]-5-(2-furyl)isoxazole-3-carboxamide::N-[1-[(4-fluorophenyl)methyl]-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide::N-[1-[(4-fluorophenyl)methyl]pyrazol-4-yl]-5-(furan-2-yl)-1,2-oxazole-3-carboxamide::SMR000308512::US10919885, Compound No. 18::cid_5082003

SMILES Fc1ccc(Cn2cc(NC(=O)c3cc(on3)-c3ccco3)cn2)cc1

InChI Key InChIKey=GELZXFQZAOXTDI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 63417   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM63417(N-[1-[(4-fluorophenyl)methyl]-4-pyrazolyl]-5-(2-fu...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetStearoyl-CoA desaturase(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM63417(N-[1-[(4-fluorophenyl)methyl]-4-pyrazolyl]-5-(2-fu...)
Affinity DataIC50: 4.50E+4nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetStearoyl-CoA desaturase 5(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM63417(N-[1-[(4-fluorophenyl)methyl]-4-pyrazolyl]-5-(2-fu...)
Affinity DataIC50: 80nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent