BDBM633575 (S) N ((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)ethyl)-1,4-oxazepane-2-carboxamide ::US11807635, Compound 1::US20240150335, Compound 6::US20250179060, Compound I

SMILES Cn1c2cc(ccc2oc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)c(F)c1

InChI Key InChIKey=ONJDRXNRBKHINH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 633575   

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633575((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2...)
Affinity DataIC50: 1.60nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633575((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2...)
Affinity DataIC50: 0.840nMAssay Description:Experimental Methods:1× activation buffer: 5 mM DTT 0.01% (V/V) Triton X-100 (preparation for current use);1× assay buffer: 50 mM NaCl 5 mM DTT 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633575((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2...)
Affinity DataIC50: 0.640nMAssay Description:Experimental Methods:1× activation buffer: 5 mM DTT 0.01% (V/V) Triton X-100 (preparation for current use);1× assay buffer: 50 mM NaCl 5 mM DTT 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633575((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2...)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent