BDBM633574 US11807624, Example 4.24

SMILES COc1cccc(OC)c1-n1c(nc(O)c(NS(=O)(=O)CCc2ncc(F)cn2)c1=O)-c1ccccc1

InChI Key InChIKey=QKCRDKRUBJBOPY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633574   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM633574(US11807624, Example 4.24)
Affinity DataEC50:  1.5nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
Go to US Patent