BDBM633276 US20190276450, Example 2.4

SMILES COCc1cc(nc(c1)[C@]1(CCOC1)OC)-c1cn(C)c2cnc(NC(C)=O)cc12

InChI Key InChIKey=GHHASQIOHFWCSO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 633276   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandPNGBDBM633276(US20190276450, Example 2.4)
Affinity DataEC50:  699nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
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