BDBM633216 US20230348473, Comp. Ex. 4

SMILES CNC(=O)c1ccc(N2CCN(Cc3cc(F)c4c5CCCc5c(=O)[nH]c4c3)CC2)c(F)n1

InChI Key InChIKey=CPBLDVOTAWHPHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 633216   

TargetPoly [ADP-ribose] polymerase 1(Human)
Xinthera

US Patent
LigandPNGBDBM633216(US20230348473, Comp. Ex. 4)
Affinity DataIC50: 8.80nMAssay Description:Compounds were dissolved in DMSO an Echo550 liquid handler was utilized to make serial dilations in the desired concentration range in Optiplate-384F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Xinthera

US Patent
LigandPNGBDBM633216(US20230348473, Comp. Ex. 4)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds were dissolved in DMSO an Echo550 liquid handler was utilized to make serial dilations in the desired concentration range in Optiplate-384F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent