BDBM633213 US20230348487, Example LS 6-48

SMILES CO[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc(Nc2ccc(N3CCOCC3)c(NC(=O)C=C)c2)ncc1Cl

InChI Key InChIKey=IGDILMSMFAWBDX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 633213   

TargetTyrosine-protein kinase JAK1(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633213(US20230348487, Example LS 6-48)
Affinity DataIC50: 2.75E+3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633213(US20230348487, Example LS 6-48)
Affinity DataIC50: 1.13E+3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633213(US20230348487, Example LS 6-48)
Affinity DataIC50: 3.87nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633213(US20230348487, Example LS 6-48)
Affinity DataIC50: 637nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633213(US20230348487, Example LS 6-48)
Affinity DataIC50: 26.1nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent