BDBM633206 US20230348487, Example LS 5-133

SMILES CN1CCN(CC1)C1CCN(CC1)c1ccc(Nc2ncc(C)c(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)n2)cc1NC(=O)C=C

InChI Key InChIKey=PHWDEPKCDQBLKI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 633206   

TargetTyrosine-protein kinase JAK1(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633206(US20230348487, Example LS 5-133)
Affinity DataIC50: 685nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633206(US20230348487, Example LS 5-133)
Affinity DataIC50: 417nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633206(US20230348487, Example LS 5-133)
Affinity DataIC50: 6.34nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633206(US20230348487, Example LS 5-133)
Affinity DataIC50: 313nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent