BDBM633205 US20230348487, Example LS 5-126

SMILES CN1CCN(CC1)C1CCN(CC1)c1ccc(Nc2ncc(Cl)cn2)cc1NC(=O)C=C

InChI Key InChIKey=LVOFKDZXLACHIF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 633205   

TargetTyrosine-protein kinase JAK1(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633205(US20230348487, Example LS 5-126)
Affinity DataIC50: 4.77E+3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633205(US20230348487, Example LS 5-126)
Affinity DataIC50: 2.09E+3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633205(US20230348487, Example LS 5-126)
Affinity DataIC50: 3.90nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633205(US20230348487, Example LS 5-126)
Affinity DataIC50: 3.12E+3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Guangzhou Salustier Biosciences

US Patent
LigandPNGBDBM633205(US20230348487, Example LS 5-126)
Affinity DataIC50: 4.35nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent