BDBM6327 6-Acetyl-8-cyclopentyl-2-[5-(2,6-dimethyl-morpholin-4-yl)-pyridin-2-ylamino]-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one::8-cyclopentyl-2-{[5-(2,6-dimethylmorpholin-4-yl)pyridin-2-yl]amino}-6-acetyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::Pyrido-[2,3-d]-pyrimidin-7-one 61

SMILES CC1CN(CC(C)O1)c1ccc(Nc2ncc3c(C)c(C(C)=O)c(=O)n(C4CCCC4)c3n2)nc1

InChI Key InChIKey=NVURUIMJTOVZJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6327   

LigandPNGBDBM6327(8-cyclopentyl-2-{[5-(2,6-dimethylmorpholin-4-yl)py...)
Affinity DataIC50: 30nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2005
Entry Details Article
PubMed
LigandPNGBDBM6327(8-cyclopentyl-2-{[5-(2,6-dimethylmorpholin-4-yl)py...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2005
Entry Details Article
PubMed