BDBM632636 US20230348450, Example 9

SMILES COC(=O)NCc1nc(C)c(s1)-c1cccc(n1)-c1ccc(C(O)=O)c(O)c1

InChI Key InChIKey=SBQHAEMSDGDWQG-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 632636   

TargetBisphosphoglycerate mutase(Human)
Genzyme

US Patent
LigandPNGBDBM632636(US20230348450, Example 9)
Affinity DataIC50: 317nMAssay Description:The following materials were used in this assay: deionized water; Bisphosphoglycerate mutase (BPGM; Standard Buffer: 50 mM Tris, 0.01% Tween 20, pH 7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetBisphosphoglycerate mutase(Human)
Genzyme

US Patent
LigandPNGBDBM632636(US20230348450, Example 9)
Affinity DataEC50:  0.460nMAssay Description:The following materials were used in this assay: Tris buffer (50 mM Tris, 0.01% Tween 20, pH 7.4); cyclohexylammonium salt of 2,3-BPG (stock solution...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetBisphosphoglycerate mutase(Human)
Genzyme

US Patent
LigandPNGBDBM632636(US20230348450, Example 9)
Affinity DataEC50:  460nMAssay Description:The following materials were used in this assay: Tris buffer (50 mM Tris, 0.01% Tween 20, pH 7.4); cyclohexylammonium salt of 2,3-BPG (stock solution...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetBisphosphoglycerate mutase(Human)
Genzyme

US Patent
LigandPNGBDBM632636(US20230348450, Example 9)
Affinity DataIC50: 320nMAssay Description:The following materials were used in this assay: deionized water; Bisphosphoglycerate mutase (BPGM; Standard Buffer: 50 mM Tris, 0.01% Tween 20, pH 7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent