BDBM631118 (1R)-N-[(3R)-2,6-Dioxopiperidin-3-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide::US11802131, Example 45

SMILES O=C(N[C@@H]1CCC(=O)NC1=O)[C@@H]1CCCc2ccccc12

InChI Key InChIKey=HJIUSPUWMFCKIL-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631118   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM631118(US11802131, Example 45 | (1R)-N-[(3R)-2,6-Dioxopip...)
Affinity DataKd:  4nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
Go to US Patent