BDBM630388 US11802110, Compound S-4.1

SMILES CC(C)C[C@H](N)C(=O)N[S@@](=O)c1ccccc1

InChI Key InChIKey=DRNKHPOTRWUVCY-UHFFFAOYSA-N

Data  1 Kd  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 630388   

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM630388(US11802110, Compound S-4.1)
Affinity DataKd:  9.13E+3nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
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Date in BDB:
12/13/2023
Entry Details
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Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 630388   

CellLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
SyringePNGBDBM630388(US11802110, Compound S-4.1)
ITC DataΔG°: -6.88kcal/mole −TΔS°: -4.75kcal/mole ΔH°: -2.33kcal/mole logk: 6.00E+3
pH: 7.5 T: 125.01°C 
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