BDBM6300 8-Cyclopentyl-7-oxo-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic Acid Ethyl Ester Hydrochloride::Pyrido-[2,3-d]-pyrimidin-7-one 34::ethyl 8-cyclopentyl-7-oxo-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidine-6-carboxylate

SMILES CCOC(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n(C2CCCC2)c1=O

InChI Key InChIKey=RBQSFMVORXJXTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6300   

LigandPNGBDBM6300(ethyl 8-cyclopentyl-7-oxo-2-{[5-(piperazin-1-yl)py...)
Affinity DataIC50: 595nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2005
Entry Details Article
PubMed
LigandPNGBDBM6300(ethyl 8-cyclopentyl-7-oxo-2-{[5-(piperazin-1-yl)py...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2005
Entry Details Article
PubMed