BDBM6298 8-Cyclopentyl-6-isobutoxy-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one hydrochloride::8-cyclopentyl-6-(2-methylpropoxy)-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::Pyrido-[2,3-d]-pyrimidin-7-one 32

SMILES CC(C)COc1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n(C2CCCC2)c1=O

InChI Key InChIKey=PYDBGKLNGZRKQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6298   

LigandPNGBDBM6298(8-cyclopentyl-6-(2-methylpropoxy)-2-{[5-(piperazin...)
Affinity DataIC50: 1.76E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2005
Entry Details Article
PubMed
LigandPNGBDBM6298(8-cyclopentyl-6-(2-methylpropoxy)-2-{[5-(piperazin...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2005
Entry Details Article
PubMed