BDBM629520 US20230339981, Example 208

SMILES FC(F)c1nccc(OC[C@@H]2CC[C@]3(COc4nc5N6C[C@H]7CC[C@H](N7)[C@H]6CCCc6nc(c(F)c(n4)c56)-c4cccc5ccc(F)c(C#C)c45)CCCN23)n1

InChI Key InChIKey=PCMRDULMNVTZDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629520   

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629520(US20230339981, Example 208)
Affinity DataIC50: 0.0900nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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