BDBM629516 US20230339981, Example 204

SMILES Oc1cc(-c2c(F)c3nc(OC[C@@]45CCCN4C[C@H](F)C5)nc4N5C[C@H]6CC[C@H](N6)[C@H]5CCc(c2Cl)c34)c2c(C#C)c(F)ccc2c1

InChI Key InChIKey=CDOUTHXHKCAAQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629516   

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629516(US20230339981, Example 204)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent