BDBM629511 US20230339981, Example 199

SMILES Fc1ccc2cccc(-c3nc4CCC[C@@H]5[C@@H]6CC[C@H](CN5c5nc(OC[C@@]78CCCN7[C@H](COc7cnnc(c7)C(F)(F)F)CC8)nc(c3F)c45)N6)c2c1C#C

InChI Key InChIKey=DPTSEGYCUIWEAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629511   

TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629511(US20230339981, Example 199)
Affinity DataIC50: 0.0700nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
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